Category: Worming
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| Category | POM-VPS |
| Temperature | Ambient |
| MA/VM/EU No: | 42058/4027 |
| Species |
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| VMD Link | https://www.vmd.defra.gov.uk/ProductInformationDatabase/product/A05037 |
| NOAH Link | https://www.noahcompendium.co.uk/?id=-456793 |
| Dosage | Dosage 0.1 ml per 5 kg live bodyweight to give 0.2 mg moxidectin/kg live bodyweight. Administration Inject subcutaneously in the neck. Use sterile 18 gauge needles or smaller, of half inch (1.5 cm) length. Ensure that the needle is inserted carefully under the skin using aseptic precautions and that product does not leak from the injection site. Be certain that the needle has penetrated the skin before delivering the dose. To ensure administration of a correct dose, bodyweight should be determined as accurately as possible; accuracy of the dosing device should be checked. If animals are to be treated collectively rather than individually, they should be grouped according to their bodyweight and dosed accordingly, in order to avoid under or over dosing. DO NOT UNDERDOSE. As with any scab treatment, underdosing can cause suppression and spread of the disease. When treating groups of animals, use only the CYDECTIN Automatic Injector and vented draw-off system. For treatment of individual sheep, a syringe not exceeding 2.5 ml and calibrated in increments of 0.1 ml should be used. Syringes must be filled from the vial through a dry, sterile draw-off needle that has been placed in the vial stopper. Vial stoppers must not be broached more than 10 times. For routine prevention of sheep scab, all sheep in the flock must be injected once. The curative treatment of scab requires two injections 10 days apart. The two injections must be given on different sides of the neck. |
| Withdrawals | Not to be used in animals that have any history of previous vaccination against footrot. It is important to treat at the recommended dosage and to avoid under-dosing since this will result in spread of sheep scab. Signs of sheep scab can be confused with chewing louse infestation, against which the product is not effective. Extensive studies in laboratory animals and cattle have shown no adverse effects during pregnancy. No known incompatibility with concurrent administration of mineral supplements or fluke treatments. Do not mix with any other veterinary medicinal products before administration. Read entire package leaflet before using this product. Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy: • Too frequent and repeated use of anthelmintics from the same class, over an extended period of time. • Underdosing, which may be due to underestimation of bodyweight, misadministration of the product, or lack of calibration of the dosing device (if any). Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used. Resistance to macrocyclic lactones has been reported in Teladorsagia in sheep in a number of countries. In 2008, throughout Europe, moxidectin resistance is very rare; it has been reported in a single case involving a levamisole, benzimidazole and ivermectin-resistant strain of Teladorsagia circumcincta. Therefore the use of moxidectin should be based on local (regional, farm) epidemiological information about susceptibility of nematodes, local history of treatments and recommendations on how to use the product under sustainable conditions to limit further selection for resistance to anthelmintics. These precautions are especially important when moxidectin is being used to control resistant strains. Withdrawal periods Meat and offal: 70 days Milk: Not for use in sheep producing milk for human consumption or industrial purposes, including the dry period. Operator warnings Care should be taken to avoid self-injection. In case of contact with skin and eyes wash affected area with clean water. Do not smoke, eat or drink while handling the product. Wash hands after use. Advice to medical practitioners: In cases of accidental self-injection treat any specific signs symptomatically. Other precautions regarding impact on the environment Moxidectin fulfils the criteria for a (very) persistent, bioaccumulative and toxic (PBT) substance; therefore, exposure of the environment to moxidectin must be limited to the extent possible. Treatments should be administered only when necessary and should be based on faecal egg counts or evaluation of the risk of infestation at the animal and/or herd level. Like other macrocyclic lactones, moxidectin has the potential to adversely affect non-target organisms: •Faeces containing moxidectin excreted onto pasture by treated animals may temporarily reduce the abundance of dung feeding organisms. Following treatment of sheep with the product, levels of moxidectin that are potentially toxic to dung fly species may be excreted over a period of more than 4 weeks and may decrease dung fly abundance during that period. It has been established in laboratory tests that moxidectin may temporarily affect dung beetle reproduction; however, studies with incurred residues indicate no long-term effects. Nevertheless, in case of repeated treatments with moxidectin (as with products of the same anthelmintic class) it is advisable not to treat animals every time on the same pasture to allow dung fauna populations to recover. •Moxidectin is inherently toxic to aquatic organisms including fish. The product should be used only according to the label instructions. Based on the excretion profile of moxidectin when administered as the injectable formulation to sheep, treated animals should not have access to watercourses during the first 11 days after treatment. |
Animally Vet Supplies is the trading name of Veterinary Meds Online Ltd.
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