Parofor 70Mg/G Soluble Powder 1Kg

Target species Pre-ruminant cattle, pig. Indications for use Treatment of gastro-intestinal infections caused by Escherichia coli susceptible to paromomycin. Contra-indications Do not use in animals with known hypersensitivity to paromomycin, other aminoglycosides or any of the excipients. Do not use in cases with impaired function of the kidneys or liver. Do not use in ruminating animals. Do not use in turkeys due to the risk of selection for antimicrobial resistance in intestinal bacteria. Special warnings for each target species None. Special precautions for use Special precautions for use in animals The uptake of medication by animals can be altered as a consequence of illness. In case of insufficient uptake of water/milk animals should be treated parenterally using a suitable injectable product following the advice of the veterinarian. The use of the product should be combined with good management practices e.g. good hygiene, proper ventilation, no overstocking. Since the product is potentially ototoxic and nephrotoxic, it is recommended to assess kidney function. Do not use in newborns (calf, piglet) due to higher absorption of paromomycin and subsequently an increased risk of oto- and nephrotoxicity. Prolonged or repeated use of the product should be avoided by improving management practices and through cleansing and disinfection. Use of the product should be based on susceptibility testing of the bacteria isolated from the animal. If this is not possible, therapy should be based on local (regional, farm level) epidemiological information about susceptibility of the target bacteria. Official, national and regional antimicrobial policies should be taken into account when the product is used. Use of the product deviating from the instructions given in the SPC may increase the prevalence of bacteria resistant to paromomycin and may decrease the effectiveness of treatment with aminoglycosides due to the potential for crossresistance. Aminoglycosides are considered as critical in human medicine. Consequently, they should not be used as a first intention treatment in veterinary medicine. Special precautions to be taken by the person administering the veterinary medicinal product to animals People with known hypersensitivity to aminoglycosides should avoid contact with the veterinary medicinal product. Personal protective equipment consisting of protective clothing and impervious gloves should be worn when handling the veterinary medicinal product. Do not eat, drink and smoke when handling the product. Wash hands after use. In case of accidental ingestion, seek medical advice immediately and show the label to the physician. When handling this product, inhalation of the dust must be avoided by wearing a disposable half-mask respirator conforming to European Standard EN 149 or a non-disposable respirator to European Standard EN 140 with a filter to EN 143. Use in a well-ventilated area. Avoid inhaling the powder while preparing the medicated water or milk replacer. Avoid contact with the skin and eyes. In the event of accidental contact with the skin or eyes, rinse with plenty of water and seek medical attention if irritation persists. Adverse reactions In rare occasions soft faeces has been observed. Aminoglycoside antibiotics such as paromomycin can cause phenomena such as oto- and nephrotoxicity. Use during pregnancy, lactation or lay Laboratory studies in rat and rabbit have not produced any evidence of teratogenic, foetoxic, maternotoxic effects. The use is not recommended during the whole pregnancy. Interactions General anaesthetics and muscle relaxing products increases the neuro-blocking effect of aminoglycosides. This may cause paralysis and apnoea. Do not use concurrently with strong diuretics and potentially oto- or nephrotoxic substances.
Vat Rate: 20%