Endospec Sc 2.5%

Target species Cattle and sheep. Indications for use A broad spectrum multi-purpose anthelmintic for the control of mature and developing immature forms of gastrointestinal roundworms, lungworms, tapeworms and adult liver fluke in cattle and sheep. The product is also ovicidal against fluke and roundworm eggs. In cattle it is active against the following species: Roundworms: Ostertagia, Haemonchus, Trichostrongylus, Nematodirus, Oesophagostomum, Bunostomum, Cooperia and Strongyloides spp. It is usually effective against inhibited larvae of Cooperia and Ostertagia. Lungworms: Dictyocaulus viviparus. Tapeworms: Moniezia spp. Adult liver fluke: Fasciola hepatica. The product is ovicidal and will kill fluke and roundworm eggs, thus reducing pasture contamination. In sheep it is active against benzimidazole-susceptible strains of the following species: Roundworms: Ostertagia, Haemonchus, Trichostrongylus, Nematodirus (including N. battus), Chabertia and Oesophagostomum. It is usually effective against inhibited larvae of Ostertagia. Lungworms: Dictyocaulus filaria. Tapeworms: Moniezia spp. Adult liver fluke: Fasciola hepatica. The product is ovicidal and will kill fluke and roundworm eggs, thus reducing pasture contamination. Contra-indications Known hypersensitivity to the active ingredient. Special warnings for each target species Cattle suffering from severe lung damage due to heavy lungworm infestation may continue to cough for some weeks after treatment. Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy: •Too frequent and repeated use of anthelmintics from the same class, over an extended period of time. •Underdosing, which may be due to underestimation of body weight, misadministration of the product, or lack of calibration of the dosing device (if any). Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used. Resistance to benzimidazoles (which includes albendazole) has been reported in Cooperia, Haemonchus, Trichostrongylus, and Teladorsagia species in small ruminants in a number of countries, including the EU. Resistance to albendazole has been reported in Cooperia and Teladorsagia species in cattle in developed countries such as New Zealand. Therefore the use of this product should be based on local (regional, farm) epidemiological information about susceptibility of nematodes and recommendations on how to limit further selection for resistance to anthelmintics. Special precautions for use in animals Not to be diluted or mixed with other products. Avoid the introduction of contamination during use. The product should only be used in areas where deficiencies of cobalt and selenium are likely to occur. If in any doubt seek the advice of a veterinary surgeon. Do not administer other cobalt and selenium supplements concurrently unless specifically advised by your veterinary surgeon. Intensive use or misuse of anthelmintics can give rise to resistance. To reduce this risk, dosing programmes should be discussed with a veterinary surgeon. Care must be taken not to damage the pharyngeal region when dosing, particularly in sheep. Special precautions to be taken by the person administering the veterinary medicinal product to animals Avoid direct contact with the product. Wear suitable protective clothing including impermeable rubber gloves. In the event of accidental eye exposure, flush eye thoroughly with running water. If irritation persists, seek medical attention. Wash hands after use. Adverse reactions None known. Use during pregnancy, lactation or lay The use of the product in breeding bulls or pregnant cattle is not expected to interfere with their reproductive performance. Do not dose ewes at the ‘fluke and worm’ dose rate (7.5 mg/kg), during tupping or for 1 month after removing the rams. Can be safely used during lactation. Interactions None known.