Corvental D 100Mg Caps 100'S

Target species Dogs. Indications for use, specifying the target species For the treatment of bronchitis and congestive heart failure in dogs. Contraindications Concurrent use of beta-sympathomimetics is contra-indicated, as additive or synergistic interactions, resulting in exaggerated side effects may result. Do not use in dogs with a known history of epileptiform seizures as convulsions have been reported in patients on theophylline treatment, often with no preceding signs of toxicity and in otherwise apparently normal animals. Special warnings for each target species None known. Special precautions for use Special precautions for use in animals Theophylline should be used with caution in patients with liver disease. If vomiting occurs, the dose should be reduced or the treatment discontinued. Special precautions to be taken by the person administering the veterinary medicinal product to animals In the case of accidental ingestion, seek medical advice immediately and show the package leaflet or the label to the physician. Adverse reactions (frequency and seriousness) The following side effects have been reported: restlessness, agitation, excitement, vomiting, diarrhoea, polydipsia, sedation, reduced appetite and polyuria. If signs of CNS excitement occur, (twitching, restlessness or convulsions) discontinue treatment immediately. Use during pregnancy, lactation or lay When theophylline is prescribed to pregnant bitches, the risk-benefit of the treatment should be assessed. Only small amounts of theophylline are excreted in milk. Interaction with other medicinal products and other forms of interaction Plasma theophylline levels may increase in patients under treatment with macrolide and fluoroquinolone antibiotics, such as erythromycin and enrofloxacin, and decrease in patients receiving phenobarbitone or phenytoin. Theophylline may reduce the convulsive threshold in patients receiving ketamine. Administration of theophylline shortly before halothane anaesthesia may result in arrhythmogenic effects.