BIMECTIN HORSE WORME APPLE SYR

les or cyathostomes unless otherwise stated. Ivermectin is not effective against the encysted larval stages of the small strongyles Coronocyclus spp. Coronocyclus coronatus Coronocyclus labiatus Coronocyclus labratus Cyathostomum spp. Cyathostomum catinatum Cyathostomum pateratum Cylicocyclus spp. Cylicocyclus ashworthi Cylicocyclus elongatus Cylicocyclus insigne Cylicocyclus leptostomum Cylicocyclus nassatus Cylicostephanus spp. Cylicostephanus calicatus Cylicostephanus goldi Cylicostephanus longibursatus Cylicostephanus minutus Cylicodontophorus spp. Cylicodontophorus bicornatus Parapoteriostomum spp. Parapoteriostomum mettami Petrovinema spp. Petrovinema poculatum Poteriostomum spp. Lungworms (adult and immatures) Dictyocaulus arnfieldi Pinworms (adult and immatures) Oxyuris equi Ascarids (adults and third & fourth stage larvae) Parascaris equorum Hairworms (adults) Trichostrongylus axei Large-mouth stomach worms (adults) Habronema muscae Neck threadworms (microfilariae) Onchocerca spp. Contra-indications None. Special warnings for each target species Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy: •Too frequent and repeated use of anthelmintics from the same class, over an extended period of time. •Underdosing, which may be due to underestimation of body weight, misadministration of the product or lack of calibration of the dosing device. Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the tests(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used. Resistance to ivermectin (an avermectin) has been reported in Parascaris equorum in horses in a number of countries, including the EU. Therefore, the use of this product should be based on local (regional, farm) epidemiological information about susceptibility of nematodes and recommendations on how to limit further selection for resistance to anthelmintics. Adverse reactions Some horses carrying heavy infection of Onchocerca microfilariae have experienced oedema and pruritus following dosing, assumed to be the result of death of large numbers of microfilariae. These signs resolve within a few days but symptomatic treatment may be advisable. Special precautions for use (i) Precautions for use in animals Special warning for non-target species: The product has been formulated for use in horses only. Cats, Dogs, especially Collies, Old English Sheepdogs and related breed or crosses, and also turtles and tortoises may be adversely affected by the concentration of ivermectin in this product if they are allowed to ingest spilled paste or have access to used syringes. Parasite resistance to any particular class of anthehelminthic may develop following frequent, repeated use of an anthehelminthic of that class. (ii) Special precautions to be taken by the person administering the veterinary medicinal product to animals Do not eat, drink or smoke while handling the product. Avoid contact with skin and eyes. If accidental skin contact occurs, wash the affected area immediately with soap and water. If accidental eye exposure occurs, flush the eyes immediately with water and, if necessary, get medical attention. Wash hands after use. Use during pregnancy, lactation or lay Do not use in mares producing milk for human consumption. Interactions The effects of GABA agonists are increased by ivermectin.
Vat Rate: 20%