Zactran 150mg/ml solution for injection for cattle 100ml

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Zactran 150mg/ml solution for injection for cattle 100ml - £ 193.50
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Zactran 150mg/ml solution for injection for cattle 50ml - £ 110.78
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Vat Rate: 20%

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Target species Cattle, sheep and pigs. Indications for use Cattle: Treatment and metaphylaxis of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus somni. The presence of disease in the herd should be established before metaphylactic use. Pigs: Treatment of swine respiratory disease (SRD) associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Haemophilus parasuis and Bordetella bronchiseptica. Sheep: Treatment of infectious pododermatitis (foot rot) associated with virulent Dichelobacter nodosus and Fusobacterium necrophorum requiring systemic treatment. Contra-indications Do not use in cases of hypersensitivity to macrolide antibiotics or to any of the excipients. Do not use this veterinary medicinal product simultaneously with other macrolides or lincosamides (see 'Interactions' section). Special warnings for each target species Cattle and pigs: None. Sheep: The efficacy of antimicrobial treatment of foot rot might be reduced by others factors, such as wet environmental conditions, as well as inappropriate farm management. Treatment of foot rot should therefore be undertaken along with other flock management tools, for example providing dry environment. Antibiotic treatment of benign foot rot is not considered appropriate. Special precautions for use in animals Use of the veterinary medicinal product should be based on susceptibility testing and take into account official and local policies on the use of antimicrobials in farm animals. Special precautions to be taken by the person administering the veterinary medicinal product to animals People with known hypersensitivity to the macrolide class should avoid contact with the veterinary medicinal product. Gamithromycin may cause irritation to eyes and/or skin. Avoid contact with skin or eyes. If eye exposure occurs, flush eyes immediately with clean water. If skin exposure occurs, wash the affected area immediately with clean water. In case of accidental self-injection, seek medical advice immediately and show the package leaflet or the label to the physician. Wash hands after use. Adverse reactions During clinical trials transient injection site swellings were observed. -Visible injection site swellings associated with occasional slight pain may develop very commonly in cattle for one day. The swellings typically resolve within 3 to 14 days but may persist in some animals for up to 35 days after treatment. -Mild to moderate injection site swelling has been reported commonly in sheep and pigs in clinical trials, with occasional slight pain evident for one day in sheep. These local reactions are transient, and typically resolve within 2 (pigs) to 4 (sheep) days. The frequency of adverse reactions is defined using the following convention: -Very common (more than 1 in 10 animals treated displaying adverse reaction(s)) -Common (more than 1 but less than 10 animals in 100 animals treated) -Uncommon (more than 1 but less than 10 animals in 1,000 animals treated) -Rare (more than 1 but less than 10 animals in 10,000 animals treated) -Very rare (less than 1 animal in 10,000 animals treated, including isolated reports). Use during pregnancy, lactation or lay Based on laboratory animal data, gamithromycin has not produced any evidence of specific developmental or reproductive effects. The safety of gamithromycin during pregnancy and lactation has not been evaluated in cattle, sheep and pigs. Use only according to the risk/benefit assessment by the responsible veterinarian. Interactions Cross resistance may occur with other macrolides. Avoid simultaneous administration of antimicrobials with a similar mode of action such as other macrolides or lincosamides.

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Please note :Trackable , Royal Mail insured up to £50.

 

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Category POM-V
Temperature Ambient
MA/VM/EU No: EU/2/08/082/001-007
Species
  • cattle
  • pig
  • sheep
VMD Link Product Information Database (defra.gov.uk)
NOAH Link https://www.noahcompendium.co.uk/?id=-454098
Dosage Amounts to be administered and administration route A single dose of 6 mg gamithromycin/kg body weight (equivalent to 1 ml/25 kg body weight) into the neck (cattle and pigs) or anterior to the shoulder (sheep). To ensure correct dose, body weight should be determined as accurately as possible to avoid underdosing. Cattle and sheep Subcutaneous injection. For treatment of cattle over 250 kg and sheep over 125 kg body weight, divide the dose so that no more than 10 ml (cattle) or 5 ml (sheep) are injected at a single site. Pigs Intramuscular injection. The injection volume should not exceed 5 ml per injection site. The cap may be safely punctured up to 60 times. For multiple vial entry, an automatic dosing device is recommended to avoid excessive broaching of the stopper. Overdose Clinical studies have demonstrated the wide margin of safety for gamithromycin injection in the target species. In young adult cattle, sheep and pig studies, gamithromycin was administered by injection at 6, 18, and 30 mg/kg (1, 3, and 5 times the recommended dose) and repeated three times at 0, 5 and 10 days (three times the recommended duration of use). Injection site reactions were noted in a dose related manner.
Withdrawals Withdrawal period(s) Meat and offal: Cattle: 64 days Sheep: 29 days Pigs: 16 days Not authorised for use in lactating animals producing milk for human consumption. Do not use in pregnant animals which are intended to produce milk for human consumption within 2 months (cows, heifers) or 1 month (ewes) of expected parturition.